Table 1.
Anthropometric parameters, BMD, and body composition before and after Trikafta
| Before | After | p Value | |
|---|---|---|---|
| Weight (kg) | 51.63 ± 10.47 | 54 ± 10.82 | 0.05 |
| Height | 162.6 ± 13.23 | 162.5 ± 13.21 | 0.46 |
| BMI (kg/m2) | 19.4 ± 2.6 | 20.3 ± 2.19 | 0.05 |
| Hip BMD (gr/cm2) | 0.73 ± 0.098 | 0.81 ± 0.12 | 0.017 |
| Spine BMD (gr/cm2) | 0.76 ± 0.14 | 0.82 ± 0.14 | 0.025 |
| Total BMC (gr) | 1795.7 ± 457.6 | 1820.6 ± 411.1 | 0.58 |
| LBM (gr) | 34770.23 ± 10521.21 | 37430.16 ± 10330.09 | 0.017 |
| % Fat | 23.13 ± 6.08 | 27.55 ± 6.54 | 0.069 |
| % Fat z‐score | −0.8 ± 0.75 | 0.46 ± 0.58 | 0.012 |
| Fat mass/height2 z‐score | −0.98 ± 0.66 | −0.04 ± 0.51 | 0.025 |
Note: Values are presented as mean ± SD; n = 8 (body composition and BMD).
Abbreviations: BMC, bone mineral content; BMD, bone mineral density; BMI, body mass index; gr, grams; LBM, lean body mass; kg, kilograms; SD, standard deviation.