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Antiviral activity of thiamyxin A–D against HCoV‐229E‐luc (red) when simultaneously determining their effect on Huh‐7.5 Fluc cells (black). Renilla luciferase serves as reporter for viral load, firefly luciferase for cell viability. Measurements performed in technical duplicates of four independent biological experiments. Non‐linear regression curves (red) are given with 95 % confidence interval (black dots). Increase in cell viability over 100 % caused by reduction in viral load.
