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Comparison of lung bacteriobiota between severe AECOPD patients requiring or not requiring invasive mechanical ventilation. (A) Boxplot of estimated α-diversity by Shannon index. (B) Boxplot of estimated α-diversity by Simpson index. (C) Boxplot of estimated α-diversity by evenness. (D) Nonmetric Bray-Curtis analysis of β-diversity. The threshold for statistical significance was P = 0.05. OTI, orotracheal intubation.
