Phylogenetic tree constructed by the maximum likelihood method reflecting the genetic relationships among all 214 E. coli strains. From inside to outside, the main branches (divided into four branches), sample source, collection time, possible infection site, sequence type (ST), phenotype, and genotype for all E. coli strains are successively listed in each layer. In the phenotype circle, we defined E. coli resistance to one, two, and three kinds of carbapenem drugs as CREC-1, CREC-2, and CREC-3, respectively.