FIG 3.

Correlation between predicted OprD loss, presence of carbapenemases, and meropenem resistance phenotype. (a) Intersection of P. aeruginosa isolates with (black circles) or without (white circles) carbapenemase and/or a disrupted OprD. Assemblies of 1,124 isolates (validation data set) were included in the analysis. (b) Approximations of meropenem MICs among a subset of 1,078 isolates with reported values. Due to differing test ranges, MIC values reported as 512, 128, 64, >32, ≥32, 24, or >16 mg/L are here summarized as >16 mg/L; >8 or ≥16 mg/L are shown as 16 mg/L, and ≤0.25 mg/L and <0.25 mg/L are shown as 0.25 mg/L and 0.1 and 0.02 mg/L, respectively, thus representing an approximation.