FIG 2.

Heterogenic CD4⁺ and CD8⁺ T-cell subset characteristics in patients with active TB. (A and B) T-SNE diagrams of single-cell profiling for each CD8⁺ (A) and CD4⁺ (B) T-cell subset across the TB (left) and healthy donor (right) groups. Each dot represents a single cell colored according to the cell-clustering information. (C and D) Stacked bar plots for CD8⁺ (C) and CD4⁺ (D) T-cell proportions across the TB (blue) and healthy donor (red) groups. (E and F) Hallmark gene set-based GSVA heatmaps in each CD8⁺ (E) and CD4⁺ (F) T-cell subset across tuberculosis and healthy donor groups.