FIG 3.

Maximum likelihood phylogeny of 1,570 MopB domain-containing members constructed using 10,000 ultrafast bootstrap approximations. This phylogeny, unlike the others, contains both genomes from cultured isolates and high-quality MAGs taken from metagenomic studies. Branches with blue circles indicate that the MopB homolog was taken from an archaeal genome or MAG. We have overlaid onto the tree topology bootstrap support at crucial nodes. The color scheme for specific MopB families is identical to the one in Fig. 1. Additionally, to emphasize the catalytic versatility of the MopB superfamily, we have highlighted all known biogeochemical cycles that each MopB family is known to mediate. Elements in green boxes are nonmetals, and elements in red boxes represent metalloids.