TABLE 2.
Correlation of PI uptake percentage from flow cytometry and plate counts for C. tropicalis ATCC 750 and C. auris IL-3331a
| Strain and sample | FC PI uptake (%) | Plate count |
|
|---|---|---|---|
| Log reduction | Reduction (%) | ||
| Candida tropicalis ATCC 750 | |||
| Unstained | 0.01 | -b | - |
| Untreated | 4.9 | - | - |
| AMB (2 mg/L) | 47.4 | 4.47 | 99.99 |
| AMB (4 mg/L) | 81.3 | 5.35 | 99.99 |
| AF4 (8 mg/L) | 90.5 | 1.05 | 91.16 |
| AF4 (16 mg/L) | 90.4 | 1.27 | 94.63 |
| C. auris IL-3331 | |||
| Unstained | 0.05 | - | - |
| Untreated | 1.7 | - | - |
| AMB (4 mg/L) | 49.9 | 4.61 | 99.99 |
| AMB (8 mg/L) | 60.3 | 2.44 | 99.64 |
| AF4 (8 mg/L) | 86.6 | 3.03 | 99.90 |
| AF4 (16 mg/L) | 97.9 | 4.08 | 99.99 |
a
FC, flow cytometry; PI, propidium iodide; AMB, amphotericin B.
b
-, not applicable.