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. 2023 Feb 27;11(2):e03637-22. doi: 10.1128/spectrum.03637-22

FIG 3.

FIG 3

Various DNA and RNA viruses can trigger the upregulation of circMerTK. (A) Expression of circMerTK was examined by RT-PCR in DF1 cell line infected with AIV H9N2 at indicated time points. (B) Expression of circMerTK was examined by RT-PCR in NIH/3T3 cell line infected with AIV H9N2 at the indicated MOIs for 14 h. (C and D) PK-15 cell line was infected with IAV PR8 at indicated time points and the expression level of circMerTK was examined by (C) RT-PCR and (D) RT-qPCR. (E and F) PK-15 cell line was infected with PRV at indicated time points, and the expression level of circMerTK was examined by (E) RT-PCR and (F) RT-qPCR. (G) A549 cell line was infected with SeV or (H) MDRV at indicated time points, and the expression level of circMerTK was examined by RT-PCR. Representative data from three independent experiments are shown. Data represent the mean values ± SD (n = 3; ***, P < 0.001; P value calculated by one-way ANOVA). AIV, avian influenza virus; PRV, pseudorabies virus; SeV, Sendai virus; MDRV, Muscovy duck reovirus; PRV-gE, PRV envelope glycoprotein; SeV-NP, SeV nucleocapsid protein; MDRV-p10.8, MDRV p10.8 protein.