TABLE 2.
Comparison of outcomes between control and intervention groups
| Outcome | Data for: |
P valuea | |
|---|---|---|---|
| Control group (n = 27) | Intervention group (n = 29) | ||
| TTOT (median [IQR] [h]) | 50.1 (29.7, 71.0) | 38.0 (31.5, 53.0) | 0.041 |
| TTAT (median [IQR] [h]) | 46.2 (24.8, 69.5) | 36.4 (27.1, 53.0) | 0.168 |
| LOS (median [95% CI] [days]) | 91.0 (17.0 to NE) | 23.0 (12.0 to 29.0) | 0.024 |
| Duration of vancomycin use (median [IQR] [h])b | 14.3 (12.0, 37.3) | 12.0 (12.0, 12.0) | 0.073 |
| Mortality (no. [%])c | 7 (26) | 3 (11) | |
| Readmission (no. [%])c | 4 (15) | 1 (4) | |
| Bacteremia relapse (no. [%])c | 3 (12) | 0 | |
a
P value for equality of group Kaplan-Meier curves.
b
Patients who received more than 1 dose of vancomycin only occurred in a subset of participants (n = 6 and n = 11 for the intervention and control groups, respectively).
c
At day 30 post completion of definitive antibiotic therapy.