TABLE 2.
Gene clusters and important genes differentially downregulated in FLL361 under both anaerobic and hydrogen peroxide stress conditions
| Gene ID | Annotation | ANa |
HPSb |
||
|---|---|---|---|---|---|
| Fold change | P value | Fold change | P value | ||
| PG_0001 | Chromosomal replication initiator protein DnaA | −2.12 | 7.46E-06 | −2.55 | 5.34E-03 |
| PG_0002 | N-acetyltransferase | −2.00 | 4.64E-03 | −2.03 | 1.35E-02 |
| PG_0185 | TonB-dependent receptor | −3.82 | 1.23E-02 | −2.36 | 6.77E-03 |
| PG_0186 | RagB/SusD family nutrient uptake outer membrane protein | −4.94 | 5.87E-03 | −2.75 | 3.34E-04 |
| PG_0195 | Rubrerythrin | −6.50 | 1.68E-02 | −17.67 | 2.93E-02 |
| PG_0506 | Gingipain R2 (RgpB) | −2.79 | 1.84E-02 | −2.76 | 3.20E-02 |
| PG_0611 | Lipoprotein | −3.87 | 2.14E-02 | −1.99 | 2.14E-02 |
| PG_0612 | Hypothetical protein | − | − | − | − |
| PG_0613 | Hypothetical protein | −4.96 | 1.17E-02 | −2.95 | 8.64E-03 |
| PG_0614 | Hypothetical protein | −5.25 | 1.01E-02 | −3.16 | 2.63E-03 |
| PG_0682 | ABC transporter permease | −1.86 | 1.66E-01 | 1.92 | 2.20E-01 |
| PG_0683 | ABC transporter permease | −2.72 | 1.53E-03 | 1.17 | 1.91E-01 |
| PG_0684 | ABC transporter permease | −2.78 | 2.33E-02 | −2.62 | 7.80E-03 |
| PG_0685 | ABC transporter ATP-binding protein | −5.81 | 3.40E-02 | −5.49 | 6.84E-03 |
| PG_1030 | T9SS C-terminal target domain-containing protein | −7.57 | 3.26E-03 | −7.57 | 1.85E-03 |
| PG_1269 | 1-pyrroline-5-carboxylate dehydrogenase | −5.33 | 1.46E-02 | −5.75 | 7.54E-03 |
| PG_2170 | Amidinotransferase | −1.78 | 1.80E-02 | −2.30 | 1.33E-02 |
| PG_2171 | Ornithine-oxo-acid transaminase | −1.74 | 6.64E-03 | −2.02 | 3.04E-02 |
| PG_1809 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma | −2.61 | 6.27E-04 | −2.94 | 1.16E-02 |
| PG_1810 | 2-oxoglutarate oxidoreductase | −2.33 | 5.27E-03 | −2.35 | 1.70E-02 |
| PG_1844 | Lysine-specific cysteine protease (Kgp) | −7.19 | 1.90E-02 | −3.38 | 2.86E-03 |
| PG_1987 | Type III-B CRISPR-associated protein Cas10/Cmr2 | −3.73 | 2.55E-02 | −1.55 | 3.30E-02 |
| PG_2024 | Gingipain R2 (RgpA) | −4.62 | 2.51E-02 | −2.84 | 2.56E-02 |
| PG_2100 | T9SS C-terminal target domain-containing protein | −2.79 | 7.90E-03 | −3.98 | 1.13E-02 |
| PG_2101 | Hypothetical protein | −3.44 | 1.37E-02 | −2.83 | 4.16E-02 |
| PG_2102 | T9SS C-terminal target domain-containing protein | −6.86 | 5.22E-03 | −4.94 | 1.10E-02 |
a
AN – anaerobic conditions.
b
HPS – hydrogen peroxide stress conditions.