FIG 2.
Schematic representation of the structure of the mcr-1- and blaCTX-M-64-surrounding sequences in plasmid p1108-MCR (MG825380). Results of sequence alignments with mcr-1- and blaCTX-Ms-associated genetic structures identified in Eshcerichia coli plasmid pA31-12 (KX034083) and E. coli plasmid pHNSHP45 (KP347127) are shown. CDSs without labels represent hypothetical proteins. The shaded parallelograms denote genetic regions that exhibit sequence homology among different segments. Light shading denotes regions with a lower level of sequence identity. Arrows indicate CDSs, with arrowheads indicating the direction of transcription: red, antibiotic resistance-encoding genes; blue, mobile elements; yellow, replication protein; gray, maintenance/stability functioning genes, or hypothetical proteins.