FIG 4.

Heat maps of the top 30 bacterial species in nasal lavage samples (NAS) (A), oropharyngeal swabs (THR) (B), and sputa (SPU) (C) collected from PI and PS patients. The color indicates the absolute abundance of a bacterial taxon in the sample’s metagenome. Sample identifiers include characters indicating (from left to right) origin (M, CF clinic in Hannover), pancreatic status (PI or PS), age group (A, 7 to 17 years; B, 18 to 27 years; C, 28 to 50 years), gender (M, male; W, female), patient number, sample number, and sample type (N, nasal lavage sample; S, sputum; T, throat swab). Absolute abundance is shown by the color code at logarithmic scale: log₁₀(RPMM + 1). A gray square indicates that the taxon was not detected in the sample.