TABLE 4.

Depletion of common members of the healthy airway metagenome in the CF sputum metagenome in the presence of CF pathogens as one of the three most abundant species

Speciesa	Depletion in presence of dominant CF pathogen(s)b
	SA	PA	SM	PA and SM	PA and SA
Eubacterium sulci	↓	↓	↓	↓	↓
Fusobacterium periodonticum	↓	↓	↓	↓	↓
Neisseria subflava	↓	↓	↓	↓	↓
Rothia aeria	↓	↓		↓
Streptococcus pneumoniae	↓		↓	↓
Streptococcus pseudopneumoniae	↓		↓	↓
Atopobium parvulum		↓		↓	↓
Gemella spp.		↓	↓	↓	↓
Prevotella spp.				↓	↓
Veillonella spp.				↓	↓
Streptococcus sanguinis					↓
Streptococcus cristatus					↓

^aOnly species with consistent patterns in all subgroup samples are included.

^bSA, S. aureus; PA, P. aeruginosa; SM, S. maltophilia.