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. 2023 Mar 30;14:1145763. doi: 10.3389/fphys.2023.1145763

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Copyright © 2023 Omi, Koneru, Lyu, Haraguchi, Kamiya and Mishina.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Micro-CT analysis for cortical compartments of the male mouse tibia at 12 weeks of age. (A) Micro-CT based 2D images of the mouse proximal tibia. Scale bar = 200 µm. (B) Bone volume (BV/TV), tissue mineral density (TMD), thickness, porosity, sub-periosteal (total) area and sub-endosteal (marrow) area were analyzed (n = 5 male for Bmpr1a ^+/− ;Osx-Cre mice, n = 6 male for Bmpr1a ^+/+ ;Osx-Cre, caBmpr1a ^wt/+ ;Osx-Cre, caBmpr1a ^+/+ ;Osx-Cre mice). **p < 0.01.