Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 30;14:1170012. doi: 10.3389/fimmu.2023.1170012

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Hawerkamp, Dyer, Patil, McElheron, O’Dowd, O’Doherty, Mhaonaigh, George, O’Halloran, Reddy, Kenny, Little, Martin-Loeches, Bergin, Kennelly, Donnelly, Bourke, Long, Sui, Doherty, Conlon, Cheallaigh and Fallon

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Relationships Between Analytes Studied and World Health Organisation Disease Severity Score. On analysing immune marker concentration (z-score), and maximal disease severity rated using the World Health Organisation (WHO) COVID-19 severity score, there were no associations observed for IL-1β, IL-4 or IL-12p70 (A) whilst a negative association was seen for TGF-β (B). All remaining 16 markers demonstrated significant correlations with WHO severity score (C), with the strongest associations observed for IL-23, IL-33, G-CSF, IL-6, IL-2 and IL-10. Data are presented for the entire cohort including controls (n = 44, WHO score = 0) and those with acute COVID-19 illness (n = 118, WHO score = 1-10).