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. 2023 Apr 14;102(15):e33432. doi: 10.1097/MD.0000000000033432

Table 4.

Univariate and multivariate analysis for overall survival (OS).

Features Median OS (month) Univariate P value Multivariate P value HR 95% CI
Age, yr .80
 ≤60 15.1
 >60 16.1
Gender .73
 Female 18.1
 Male 15.2
Smoking status .27
 Never smoked NA
 Ex-smoker 16.1
 Current smoker 15.2
Stage at diagnosis .01 .08 4.18 (0.84–19.7)
 Limited-stage 23.0
 Extensive-stage 15.1
ECOG PS .34
 0 15.1
 1 17.0
 2 NA
Brain metastasis at diagnosis .22
 Present 15.2
 Absent 16.6
PCI .06
 Absent 11.3
 Present 16.6
No. of metastatic site .83
 1 16.1
 2 16.9
 3 15.1
 4 15.2
Liver metastasis .61
 Present 15.2
 Absent 16.6
NLR .006 .34 0.57 (0.18–1.82)
 ≤3.43 16.9
 >3.43 11.3
PLR .007 .58 0.71 (0.21–2.34)
 ≤135.7 16.9
 >135.7 11.5

Statistically significant values are marked with bold.

CI = confidence interval, ECOG PS = Eastern Cooperative Oncology Group performance status, HR = hazard ratio, NA = not applicable, NLR = neutrophil-lymphocyte ratio, NR = not reached, PCI = prophylactic cranial irradiation, PLR = platelet-lymphocyte ratio