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. 2023 Apr 13;18(4):e0283192. doi: 10.1371/journal.pone.0283192

Table 3. Univariate Cox regression analysis of prognostic factors in matched population.

Variables CSS OS
HR 95%CI P HR 95%CI P
Age
<62
≥62 1.502 0.825–2.734 0.183 2.843 1.989–4.063 <0.001***
gender
Men/Women 1.542 0.847–2.809 0.156 1.340 0.937–1.918 0.109
Race
White 1 1
Black 0.693 0.327–1.469 0.338 1.109 0.650–1.892 0.705
Others 0.980 0.365–2.633 0.968 1.163 0.720–1.879 0.537
Marital status
Married/Not married 1.314 0.658–2.147 0.208 1.142 0.613–1.793 0.614
Tumor extent
Adjacent connective tissue 1 1
Adjacent organs or structures 4.130 1.922–8.874 <0.001*** 2.271 1.534–3.362 <0.001***
WHO classification
nontype B3/type B3 1.177 0.754–1.836 0.474 1.039 0.794–1.359 0.780
Lymph node status
Negative/Positive 0.392 0.054–2.847 0.355 0.731 0.298–1.789 0.492
Extent of surgery
Radical surgery 1 1
Total resection 0.966 0.438–2.130 0.932 0.787 0.513–1.209 0.275
Simple or partial resection 1.851 0.839–4.082 0.127 1.363 0.878–2.117 0.167
Debulking surgery 3.248 0.893–9.816 0.074 1.215 0.433–3.413 0.711
PORT
Yes/No 2.860 1.723–4.747 <0.001*** 1.602 1.188–2.159 0.002**

Abbreviations: HR, hazard ratio; CI, confidence interval; CSS, cancer-specific survival; OS, overall survival; WHO, World Health Organization; PORT, postoperative radiotherapy.