Table 3. Univariate Cox regression analysis of prognostic factors in matched population.
Variables | CSS | OS | ||||
---|---|---|---|---|---|---|
HR | 95%CI | P | HR | 95%CI | P | |
Age | ||||||
<62 | ||||||
≥62 | 1.502 | 0.825–2.734 | 0.183 | 2.843 | 1.989–4.063 | <0.001*** |
gender | ||||||
Men/Women | 1.542 | 0.847–2.809 | 0.156 | 1.340 | 0.937–1.918 | 0.109 |
Race | ||||||
White | 1 | 1 | ||||
Black | 0.693 | 0.327–1.469 | 0.338 | 1.109 | 0.650–1.892 | 0.705 |
Others | 0.980 | 0.365–2.633 | 0.968 | 1.163 | 0.720–1.879 | 0.537 |
Marital status | ||||||
Married/Not married | 1.314 | 0.658–2.147 | 0.208 | 1.142 | 0.613–1.793 | 0.614 |
Tumor extent | ||||||
Adjacent connective tissue | 1 | 1 | ||||
Adjacent organs or structures | 4.130 | 1.922–8.874 | <0.001*** | 2.271 | 1.534–3.362 | <0.001*** |
WHO classification | ||||||
nontype B3/type B3 | 1.177 | 0.754–1.836 | 0.474 | 1.039 | 0.794–1.359 | 0.780 |
Lymph node status | ||||||
Negative/Positive | 0.392 | 0.054–2.847 | 0.355 | 0.731 | 0.298–1.789 | 0.492 |
Extent of surgery | ||||||
Radical surgery | 1 | 1 | ||||
Total resection | 0.966 | 0.438–2.130 | 0.932 | 0.787 | 0.513–1.209 | 0.275 |
Simple or partial resection | 1.851 | 0.839–4.082 | 0.127 | 1.363 | 0.878–2.117 | 0.167 |
Debulking surgery | 3.248 | 0.893–9.816 | 0.074 | 1.215 | 0.433–3.413 | 0.711 |
PORT | ||||||
Yes/No | 2.860 | 1.723–4.747 | <0.001*** | 1.602 | 1.188–2.159 | 0.002** |
Abbreviations: HR, hazard ratio; CI, confidence interval; CSS, cancer-specific survival; OS, overall survival; WHO, World Health Organization; PORT, postoperative radiotherapy.