Figure 3.

Association between gout and all-cause mortality among HD and PD patients. Binary exposure definitions: (1) Gout1: active Rx for colchicine or feboxustat; (2) Gout2: active Rx for colchicine or feboxustat or allopurinol; and (3) Gout3: active Rx for colchicine or feboxustat or allopurinol; or prior diagnosis of gout. Cox models were stratified by study phase and EHR data source, and propensity-score matched 1:1 with progressive covariate adjustments model 1: unadjusted; model 2: age only; model 3: model 2 + other demographics, including sex, Black race, BMI, and dialysis vintage; model 4: model 3 + 13 comorbidities; model 5: model 4 adjustments+albumin, creatinine, and phosphorus; model 6 (HD only): model 5 adjustments+vascular access type. Estimates from the fully adjusted models are reported. BMI, body mass index.