Table 1.
Patient characteristics in hemodialysis and peritoneal dialysis patients, with and without gout, before propensity score matching
| Characteristics | HD | PD | ||
|---|---|---|---|---|
| No Gout | Gout | No Gout | Gout | |
| Number of patients | 60,888 | 9409 | 4057 | 1060 |
| Demographics | ||||
| Patient age, yr | 63.2 (14.9) | 69.1 (12.8) | 56.2 (15.3) | 62.6 (13.7) |
| Male | 55% | 64% | 53% | 69% |
| Black race | 39% | 35% | 27% | 25% |
| BMI, kg/m2 | 28.3 (7.1) | 30.0 (7.3) | 29.0 (6.5) | 30.3 (6.2) |
| Time on dialysis, years | 3.35 (4.04) | 2.27 (2.97) | 2.63 (3.39) | 2.20 (2.83) |
| Comorbidity history | ||||
| Coronary artery disease | 19% | 26% | 18% | 25% |
| Cancer (nonskin) | 5% | 9% | 5% | 10% |
| Other cardiovascular disease | 16% | 26% | 10% | 15% |
| Cerebrovascular disease | 6% | 7% | 4% | 6% |
| Congestive heart failure | 24% | 32% | 12% | 16% |
| Diabetes | 66% | 64% | 52% | 48% |
| Gastrointestinal bleeding | 4% | 4% | 1% | 3% |
| Hypertension | 79% | 83% | 75% | 79% |
| Lung disease | 7% | 11% | 4% | 6% |
| Neurologic disease | 5% | 6% | 2% | 3% |
| Psychiatric disorder | 24% | 25% | 19% | 19% |
| Peripheral vascular disease | 12% | 14% | 9% | 10% |
| Recurrent cellulitis/gangrene | 5% | 5% | 2% | 2% |
| Dialysis treatments | ||||
| Vascular access type | ||||
| Catheter | 41% | 37% | ||
| Fistula | 47% | 51% | ||
| Graft | 13% | 12% | ||
| Single-pool Kt/V | 1.54 (0.28) | 1.53 (0.28) | ||
| Laboratory results | ||||
| Phosphorus, mg/dl | 5.19 (1.64) | 5.06 (1.49) | 5.31 (1.56) | 5.08 (1.44) |
| Albumin, g/dl | 3.63 (0.49) | 3.65 (0.46) | 3.51 (0.47) | 3.54 (0.43) |
| PTH, pg/ml | 322 [188–535] | 312 [187–500] | 358 [210–556] | 346 [206–520] |
| Creatinine, mg/dl | 7.57 (3.07) | 7.11 (2.90) | 9.04 (4.30) | 8.62 (4.14) |
| Hemoglobin, g/dl | 10.5 (1.4) | 10.6 (1.4) | 11.0 (1.5) | 11.1 (1.5) |
| Ferritin, ng/ml | 615 [338–948] | 603 [328–941] | 582 [300–933] | 549 [271–939] |
| White blood cell count, 103 cells/mm3 | 6.7 [5.4–8.4] | 6.8 [5.4–8.5] | 7.2 [5.7–9.2] | 7.3 [5.7–9.2] |
Gout: active Rx for colchicine or febuxostat or allopurinol; or prior diagnosis of gout (Gout3); mean (SD), median [interquartile range], or % shown. Most variables had missingness <15%, with exception of Black (18%), VA type (16%), and single-pool Kt/V (27%) in HD, and BMI (28%), PTH (17%), and white blood cell count (23%) in PD patients. HD, hemodialysis; PD, peritoneal dialysis; PTH, parathyroid hormone; BMI, body mass index.