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Testican-2 levels and risk of incident ESKD. Cubic spline plots showing the association between baseline testican-2 levels and incident ESKD in fully adjusted Cox proportional hazards models in AASK (A), the CRIC study (B), and the ARIC study (C). The left y-axes denote the HR for incident ESKD at each testican-2 level and correspond to the cubic spine plots. The right y-axes denote the frequency (number of study participants) at each testican-2 level and correspond to the histograms.
