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. 2023 Jan 26;4(1):119–120. doi: 10.34067/KID.0000000000000023

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Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Nephrology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Light microscopy and immunohistochemistry images. (A) Hematoxylin and eosin staining, magnification ×20: Renal allograft biopsy shows interstitial lymphoplasmacytic infiltrate with few neutrophils surrounding infected tubules. These are infiltrated by lymphocytes (black arrows), and infected tubular epithelial cells are characterized by a homogenous intranuclear inclusion of BKPyV (red arrows). (B) Immunohistochemistry, magnification ×15: This BKPyV infection was confirmed by SV40 immunohistochemistry which reveal by nuclear labeling the infected cells close to other healthy ones. (C) Immunohistochemistry, magnification ×33: Detection of a simultaneous infection by cytomegalovirus, proven by immunohistochemistry revealing rare nuclear positivity in glomerular cell.