Table 1.
Patient characteristics, separated by iGFR category (<45, 45–60, 60–90, >90)
| iGFR | ||||
|---|---|---|---|---|
| <45 | 45–60 | 60–90 | >90 | |
| N | 10 | 12 | 17 | 11 |
| Furosemide kidney clearance (ml/min)a | 45.6 (23.9) | 72.9 (30.8) | 125.6 (47.4) | 205.1 (61.3) |
| Age (yr)a | 61.8 (11.8) | 63.2 (11.6) | 54.2 (9.2) | 44.9 (13.2) |
| Female (%) | 4 (40) | 5 (41.7) | 3 (17.6) | 4 (36.4) |
| Race (%) | ||||
| Black or African American | 1 (10) | 3 (25) | 9 (52.9) | 5 (45.5) |
| White or Caucasian | 7 (70) | 9 (75) | 8 (47.1) | 6 (54.5) |
| Other/prefer not to answer | 2 (20) | 0 (0) | 0 (0) | 0 (0) |
| BMI (kg/m2)a | 27.2 (9.4) | 30.3 (7.6) | 31.6 (4.6) | 28.9 (4.6) |
| Education history (%) | ||||
| Less than high school | 0 (0) | 1 (8.3) | 0 (0) | 1 (9.1) |
| High school graduate | 2 (20) | 1 (8.3) | 6 (35.3) | 2 (18.2) |
| Some college | 5 (50) | 3 (25) | 4 (23.5) | 4 (36.4) |
| College graduate or higher | 3 (30) | 7 (58.3) | 7 (41.2) | 4 (36.4) |
| Smoking (%) | 3 (30) | 2 (16.7) | 5 (29.4) | 4 (36.4) |
| Diabetes (%) | 2 (20) | 3 (25) | 0 (0) | 1 (9.1) |
| CHF (%) | 0 (0) | 1 (8.3) | 1 (5.9) | 0 (0) |
| SBP (mm Hg)a | 142.3 (28) | 131.9 (13.8) | 139.1 (19.6) | 124.1 (14.8) |
| Urine albumin (mg/mg, spot)a | 34.4 (30.8) | 2.2 (4.9) | 10.7 (25.9) | 9.8 (21.2) |
| Serum albumin (g/dl)a | 4 (0.3) | 4.2 (0.2) | 3.9 (0.4) | 4.2 (0.3) |
| Medication use (%) | ||||
| Insulin | 0 (0) | 2 (16.7) | 0 (0) | 1 (9.1) |
| Statin | 5 (50) | 6 (50) | 5 (29.4) | 1 (9.1) |
| ACE inhibitor | 2 (20) | 4 (33.3) | 4 (23.5) | 1 (9.1) |
| Thiazide diuretic | 1 (10) | 0 (0) | 2 (11.8) | 0 (0) |
| Beta blocker | 0 (0) | 2 (16.7) | 2 (11.8) | 0 (0) |
Continuous variables are expressed as mean (standard deviation) and categorical variables as N (%). iGFR, iohexol GFR; BMI, body mass index; CHF, congestive heart failure; SBP, systolic BP.
a
Expressed as mean (standard deviation).