Table 2.
Comparison of optimized plans (Opt) for validation to corresponding clinical (Clin) plans, predicted (Pred) doses to clinical plans, automated (Auto) plans to predicted doses, and automated plans to clinical plans, along with optimization times for optimized and automated plans.
| Mean Absolute Differences | Mean Differences | DSC | Mean (Range) | |||
|---|---|---|---|---|---|---|
| Dwell Times | Overall Dosea | Dwell Times | Overall Dose | 100% Isodose | Optimization Time | |
| s (%b) | cGy (%) | s | cGy (%) | s | ||
| Optimized Plan Results for Validation (Clin-Opt) | ||||||
|
| ||||||
| T&O | 4.1 (0.9%) | 6.9 (1.1%) | 0.3 | 1.8 (0.3%) | 0.99 | 75 (63-96) |
| T&O + N | 5.6 (1.0%) | 8.9 (1.3%) | 0.2 | 1.7 (0.3%) | 0.98 | 124 (80-227) |
| T&R | 2.7 (0.7%) | 6.1 (0.8%) | 0.2 | 1.3 (0.2%) | 0.98 | 90 (69-126) |
| T&R + N | 4.0 (0.7%) | 7.6 (1.0%) | 0.2 | 2.0 (0.3%) | 0.99 | 113 (94-130) |
| Automated Plan Results (All T&O) | ||||||
|
| ||||||
| Clin-Pred | NA | 57.6 (9.1%) | NA | 9.4 (1.7%) | 0.90 | NA |
| Pred-Auto | NA | 38.8 (6.1%) | NA | −15.5 (−2.5%) | 0.96 | 81 (70-92) |
| Clin-Auto | 10.3 (2.1%) | 40.9 (6.5%) | 0.0 | −6.2 (−0.8%) | 0.91 | 81 (70-92) |
T&O = tandem-and-ovoid, T&R = tandem-and-ring, N = needle(s), DSC = Dice similarity coefficient.
a
Over all voxels for each patient, where % is relative to prescription
b
Relative to the total plan dwell time (corresponding values for mean differences were less than 0.1% so are not shown)