Table 4.

Comparison of EQD2 dose metrics for automated plans compared to clinical plans. EQD2 incorporates the prior external beam radiotherapy dose and was computed assuming the dose for the single brachytherapy fraction was delivered for the entire course of treatment.

	HRCTV D90 [Gy]		Bladder D2cc [Gy]		Rectum D2cc [Gy]		Sigmoid D2cc [Gy]
Subject	Auto	Clinical	Auto	Clinical	Auto	Clinical	Auto	Clinical
1*	92.6	84.2**	59.1	56.7	71.7	63.6	77.4*	72.2
2*	97.7	85.5	96.7*	80.0	82.8*	73.4	75.9*	73.5
3*	98.2	96.6	95.9*	95.9*	80.8*	80.0*	73.9	72.7
4**	83.5**	84.4*	85.8	88.6	71.9	65.1	53.6	54.8
5	86.3	89.7	84.1	89.1	58.6	60.2	53.9	57.1
6*	99.2	96.3	60.6	59.2	68.0	65.5	78.0*	75.2*
7**	81.3**	79.8**	58.6	56.2	67.4	65.4	67.4	65.7
8**	81.5**	85.0	87.1	88.6	68.6	72.5	63.7	62.2
9*	111.0	90.5	79.6	72.4	55.3	54.9	77.1*	69.3
10	94.9	104.1	71.4	77.8	58.0	59.1	67.4	71.5

^*indicates the dose metric exceeded a hard maximum planning constraint (bladder D_2cc > 90 Gy, rectum D_2cc > 75 Gy, sigmoid D_2cc > 75 Gy), while

^**indicates that the minimum HRCTV coverage D90 constraint (85 Gy) was not met.

Stars in the left column indicate whether the automated plan was generally too hot (*) or too cold (**).