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. 2023 Apr 3;55(4):559–567. doi: 10.1038/s41588-023-01343-9

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© The Author(s) 2023, corrected publication 2023

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Extended Data Fig. 2 — The sum of all probabilities for each index SNP is 1. Lines are colored according to the axis they belong to. All points in a horizontal line (green) have the same probability of ‘fetal-only effect’, points on a line (yellow) parallel to the right side of the triangle have the same probability of a ‘Maternal-only effect’, and lines (black) parallel to the left side of the triangle have the same probability of a ‘Maternal and fetal effect’. Probabilities were obtained using Gaussian Mixture models clustering using the effect size and standard error estimates of the parental transmitted and nontransmitted alleles (n = 136,833 parent-offsprings). While five different clusters were identified, the fetal effect was broken down into two groups (parent-of-origin and independent of parent-of-origin), and the maternal and fetal effects also into two groups (same or opposite maternal and fetal direction). For this figure, probability of a ‘Fetal only effect’ is the sum of the two groups with fetal effect, and ‘Maternal and fetal effect’ is the sum of the probabilities of the two clusters with maternal and fetal effects.