Table 3.

Adjusted odds ratios and 95% confidence intervals of the associations of trimester-specific prenatal BPA and BPS with atopic disease outcomes at age 6 estimated from a generalized estimation equation

		Wheezea	Ever Asthmab	Current Asthmab	Food Allergyc
First trimester
All	BPA	0.95 (0.76, 1.19)	1.02 (0.79, 1.32)	1.06 (0.81, 1.38)	0.78 (0.64, 0.95)*
	BPS	0.98 (0.56, 1.72)	0.72 (0.38, 1.33)	1.18 (0.60, 2.31)	0.85 (0.45, 1.59)
Males	BPA	0.75 (0.54, 1.05)	0.89 (0.64, 1.22)	0.94 (0.69, 1.27)	0.82 (0.59, 1.14)
	BPS	0.85 (0.40, 1.80)	1.01 (0.44, 2.28)	1.93 (0.73, 5.09)	0.79 (0.29, 2.19)
Females	BPA	1.12 (0.80, 1.57)	1.21 (0.73, 2.03)	1.29 (0.80, 2.08)	0.69 (0.52, 0.90)*
	BPS	1.12 (0.47, 2.69)	0.41 (0.15, 1.13)	0.55 (0.19, 1.57)	0.81 (0.34, 1.96)
Second trimester
All	BPA	0.93 (0.70, 1.24)	0.91 (0.68, 1.21)	0.89 (0.63, 1.26)	1.27 (1.02, 1.58)*
	BPS	1.12 (0.51, 2.44)	1.10 (0.49, 2.49)	1.03 (0.37, 2.85)	0.92 (0.42, 2.02)
Males	BPA	1.31 (0.87, 1.97)	1.13 (0.82, 1.55)	1.03 (0.71, 1.49)	1.48 (1.02, 2.14)*
	BPS	1.44 (0.46, 4.54)	0.84 (0.27, 2.59)	0.79 (0.19, 3.34)	1.12 (0.35, 3.60)
Females	BPA	0.72 (0.47, 1.09)	0.65 (0.35, 1.20)	0.66 (0.38, 1.16)	1.22 (0.91, 1.65)
	BPS	1.06 (0.31, 3.62)	2.13 (0.57, 7.98)	1.93 (0.39, 9.51)	1.02 (0.35, 3.02)
Third trimester
All	BPA	1.01 (0.79, 1.29)	0.91 (0.68, 1.20)	1.07 (0.81, 1.40)	1.18 (0.93, 1.48)
	BPS	0.86 (0.45, 1.64)	1.07 (0.52, 2.21)	0.99 (0.42, 2.33)	0.69 (0.32, 1.48)
Males	BPA	1.19 (0.84, 1.68)	0.94 (0.66, 1.34)	1.18 (0.83, 1.67)	1.33 (0.95, 1.87)
	BPS	0.93 (0.39, 2.20)	0.96 (0.37, 2.51)	0.86 (0.28, 2.71)	0.46 (0.13, 1.66)
Females	BPA	0.93 (0.65, 1.32)	0.88 (0.51, 1.54)	0.86 (0.57, 1.30)	1.16 (0.84, 1.60)
	BPS	0.76 (0.28, 2.06)	11.30 (0.42, 4.03)	1.01 (0.27, 3.80)	0.99 (0.38, 2.63)

^aall n=487; males n=227; females n=260

^ball n=491; males n=229; females n=262

^call n=501; males n=232; females n=269

^*Statistically significant at p<0.05