Table 1.

FRET analysis of G-quadruplex melting temperatures in the presence of tested compounds at a concentration of 2 μM.

Compound	Tm (°C)	ΔTm (°C)
3	61 ± 0.1	10
6	65 ± 0.1	14
12	79 ± 0.2	28
14	64 ± 0.2	13
15	70 ± 1.0	19
PDS	93 ± 13	42
PBS	51 ± 0.1	0

PDS (pyridostatin)—positive control, PBS (buffer)—negative control. The ΔT_m was calculated by subtracting the average T_m of PBS (control) from average T_m for each compound. The T_m results were averaged from three independent experiments, depicted as mean and standard error.