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. 2023 Apr 13;13:6023. doi: 10.1038/s41598-023-33245-5

Table 2.

Baseline characteristics of enrolled participants with pulmonary and extrapulmonary tuberculosis stratified by sex.

Variables Pulmonary tuberculosis Extrapulmonary tuberculosis
Total (n = 4636) Male (n = 2898) Female (n = 1738) P-value Total (n = 1321) Male (n = 669) Female (n = 652) P-value
Age, years 58.8 ± 19.6 57.8 ± 17.9 60.5 ± 22.0  < 0.001 54.8 ± 20.5 54.1 ± 20.1 55.4 ± 20.9 0.254
Body mass index (kg/m2) 21.3 ± 3.4 21.4 ± 3.3 21.1 ± 3.4 0.038 22.7 ± 3.6 23.1 ± 3.4 22.4 ± 3.7  < 0.001
Smoking status  < 0.001  < 0.001
 Current smoker 1016 (21.9) 948 (32.7) 68 (3.9) 166 (12.6) 149 (22.3) 17 (2.6)
Drinking status  < 0.001  < 0.001
 Heavy drinker 312 (7.6) 294 (11.5) 18 (1.2) 48 (4.2) 44 (7.7) 4 (0.7)
Comorbidity 0.084 0.010
 Yes 2738 (59.1) 1740 (60.1) 998 (57.5) 721 (54.6) 389 (58.1) 332 (50.9)
Types of comorbidities
 Diabetes 956 (20.6) 652 (22.5) 304 (17.5)  < 0.001 210 (15.9) 125 (18.7) 85 (13.0) 0.006
 Chronic lung disease 238 (5.1) 164 (5.7) 74 (4.3) 0.043 39 (3.0) 30 (4.5) 9 (1.4) 0.002
 Chronic heart disease 221 (4.8) 138 (4.8) 83 (4.8)  > 0.999 63 (4.8) 38 (5.7) 25 (3.8) 0.149
 Chronic liver disease 96 (2.1) 75 (2.6) 21 (1.2) 0.002 31 (2.3) 22 (3.3) 9 (1.4) 0.035
 Chronic kidney disease 130 (2.8) 91 (3.1) 39 (2.2) 0.090 68 (5.1) 47 (7.0) 21 (3.2) 0.003
 Chronic brain disease 396 (8.5) 207 (7.1) 189 (10.9)  < 0.001 118 (8.9) 63 (9.4) 55 (8.4) 0.597
 Malignancy 456 (9.8) 341 (11.8) 115 (6.6)  < 0.001 116 (8.8) 63 (9.4) 53 (8.1) 0.465
 Autoimmune disease 53 (1.1) 27 (0.9) 26 (1.5) 0.108 14 (1.1) 6 (0.9) 8 (1.2) 0.751
Initial presenting symptoms 0.851 0.004
 Yes 2580 (65.5) 1663 (65.4) 917 (65.6) 952 (72.1) 506 (75.6) 446 (68.4)
Chest radiograph findings
 Cavitation 869 (19.2) 651 (23.0) 218 (12.9)  < 0.001
 Bilateral infiltrations 1435 (32.7) 955 (34.6) 480 (29.5) 0.001
Sputum AFB test results
 AFB smear positivity 1182 (29.3) 793 (31.0) 389 (26.3) 0.002
 AFB culture positivity 2422 (60.9) 1538 (61.0) 884 (60.8) 0.902

AFB acid-fast bacilli.