TABLE 2.
Matrix of pairwise comparisons on total blood loss (L) in intravenous (g) administration (shown as mean difference and 95% confidence intervals)
| 1.0 g TXA IV | 14.0 g EACA IV | 1.5 g TXA IV | 2.0 g TXA IV | 5.0 g EACA IV | 6.0 g TXA IV | Placebo | |
|---|---|---|---|---|---|---|---|
| 1.0 g TXA IV | 1 | −0.187 (−0.508, 0.139) | −0.062 (−0.363, 0.242) | −0.331 (−0.537, −0.121) | −0.101 (−0.423, 0.224) | −0.248 (−0.504, 0.015) | 0.279 (0.174, 0.389) |
| 14.0 g EACA IV | 0.187 (−0.139, 0.508) | 1 | 0.125 (−0.297, 0.545) | −0.144 (−0.393, 0.104) | 0.086 (−0.263, 0.438) | −0.061 (−0.452, 0.331) | 0.465 (0.154, 0.778) |
| 1.5 g TXA IV | 0.062 (−0.242, 0.363) | −0.125 (−0.545, 0.297) | 1 | −0.27 (−0.609, 0.071) | −0.039 (−0.459, 0.381) | −0.186 (−0.551, 0.181) | 0.341 (0.058, 0.625) |
| 2.0 g TXA IV | 0.331 (0.121, 0.537) | 0.144 (−0.104, 0.393) | 0.27 (−0.071, 0.609) | 1 | 0.23 (−0.018, 0.478) | 0.083 (−0.218, 0.386) | 0.61 (0.421, 0.8) |
| 5.0 g EACA IV | 0.101 (−0.224, 0.423) | −0.086 (−0.438, 0.263) | 0.039 (−0.381, 0.459) | −0.23 (−0.478, 0.018) | 1 | −0.147 (−0.537, 0.244) | 0.38 (0.069, 0.692) |
| 6.0 g TXA IV | 0.248 (−0.015, 0.504) | 0.061 (−0.331, 0.452) | 0.186 (−0.181, 0.551) | −0.083 (−0.386, 0.218) | 0.147 (−0.244, 0.537) | 1 | 0.527 (0.29, 0.763) |
| Placebo | −0.279 (−0.389, −0.174) | −0.465 (−0.778, −0.154) | −0.341 (−0.625, −0.058) | −0.61 (−0.8, −0.421) | −0.38 (−0.692, −0.069) | −0.527 (−0.763, −0.29) | 1 |
Note: Bold results mean statistically significance.
Abbreviations: IA, intra‐articular; TXA, tranexamic acid; EACA, aminocaproic acid.