TABLE 3.
Matrix of pairwise comparisons on total blood loss (L) in intravenous (mg/kg) administration (shown as mean difference and 95% confidence intervals)
| 10 mg/kg TXA IV | 150 mg/kg EACA IV | 15 mg/kg TXA IV | 20 mg/kg TXA IV | 30 mg/kg TXA IV | Placebo | |
|---|---|---|---|---|---|---|
| 10 mg/kg TXA IV | 1 | −0.474 (−0.894, −0.038) | 0.017 (−0.236, 0.32) | −0.024 (−0.264, 0.224) | −0.075 (−0.329, 0.164) | 0.205 (−0.029, 0.466) |
| 150 mg/kg EACA IV | 0.474 (0.038, 0.894) | 1 | 0.493 (0.117, 0.882) | 0.45 (0.05, 0.841) | 0.398 (−0.007, 0.779) | 0.68 (0.326, 1.036) |
| 15 mg/kg TXA IV | −0.017 (−0.32, 0.236) | −0.493 (−0.882, −0.117) | 1 | −0.04 (−0.289, 0.166) | −0.089 (−0.324, 0.073) | 0.189 (0.026, 0.327) |
| 20 mg/kg TXA IV | 0.024 (−0.224, 0.264) | −0.45 (−0.841, −0.05) | 0.04 (−0.166, 0.289) | 1 | −0.05 (−0.271, 0.145) | 0.229 (0.056, 0.422) |
| 30 mg/kg TXA IV | 0.075 (−0.164, 0.329) | −0.398 (−0.779, 0.007) | 0.089 (−0.073, 0.324) | 0.05 (−0.145, 0.271) | 1 | 0.278 (0.127, 0.476) |
| Placebo | −0.205 (−0.466, 0.029) | −0.68 (−1.036, −0.326) | −0.189 (−0.327, −0.026) | −0.229 (−0.422, −0.056) | −0.278 (−0.476, −0.127) | 1 |
Note: Bold results mean statistically significance.
Abbreviations: IA, intra‐articular; TXA, tranexamic acid; EACA, aminocaproic acid.