TABLE 5.
Matrix of pairwise comparisons on HB drop (g/dL) in intravenous (g) administration (shown as mean difference and 95% confidence intervals)
| 10.0 g EACA IV | 1.0 g TXA IV | 14.0 g EACA IV | 2.0 g TXA IV | 5.0 g EACA IV | Placebo | |
|---|---|---|---|---|---|---|
| 10.0 g EACA IV | 1 | −0.22 (−0.52, 0.06) | −0.42 (−1.28, 0.46) | −0.25 (−0.97, 0.48) | −0.05 (−0.88, 0.8) | 0.44 (0.2, 0.73) |
| 1.0 g TXA IV | 0.22 (−0.06, 0.52) | 1 | −0.19 (−1.05, 0.67) | −0.02 (−0.73, 0.7) | 0.17 (−0.65, 1.02) | 0.67 (0.48, 0.9) |
| 14.0 g EACA IV | 0.42 (−0.46, 1.28) | 0.19 (−0.67, 1.05) | 1 | 0.17 (−0.3, 0.64) | 0.37 (−0.27, 1.01) | 0.87 (0.04, 1.71) |
| 2.0 g TXA IV | 0.25 (−0.48, 0.97) | 0.02 (−0.7, 0.73) | −0.17 (−0.64, 0.3) | 1 | 0.2 (−0.23, 0.64) | 0.7 (0.01, 1.39) |
| 5.0 g EACA IV | 0.05 (−0.8, 0.88) | −0.17 (−1.02, 0.65) | −0.37 (−1.01, 0.27) | −0.2 (−0.64, 0.23) | 1 | 0.5 (−0.31, 1.31) |
| Placebo | −0.44 (−0.73, −0.2) | −0.67 (−0.9, −0.48) | −0.87 (−1.71, −0.04) | −0.7 (−1.39, −0.01) | −0.5 (−1.31, 0.31) | 1 |
Note: Bold results mean statistically significance.
Abbreviations: IA, intra‐articular; TXA, tranexamic acid; EACA, aminocaproic acid.