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. 2023 Mar 6;15(4):930–946. doi: 10.1111/os.13678

TABLE 8.

Matrix of pairwise comparisons on transfusion rates in intravenous (g) administration (shown as odds ratios and 95% confidence intervals)

1.0 g TXA IV 2.0 g TXA IV 5.0 g EACA IV 10.0 g EACA IV 14.0 g EACA IV Placebo
1.0 g TXA IV 1 0.19 (0, 4.49) 0.17 (0, 34.84) 0.58 (0.1, 2.64) 0.04 (0, 4.1) 5.01 (1.53, 17.07)
2.0 g TXA IV 5.29 (0.22, 294.29) 1 0.99 (0.02, 61.65) 3.02 (0.11, 165.14) 0.26 (0, 5.89) 26.44 (1.46, 1255.83)
5.0 g EACA IV 5.73 (0.03, 1598.32) 1.01 (0.02, 62.88) 1 3.28 (0.01, 849.81) 0.25 (0, 45.47) 28.86 (0.17, 7239.88)
10.0 g EACA IV 1.72 (0.38, 10.23) 0.33 (0.01, 9.2) 0.31 (0, 68.22) 1 0.08 (0, 8.13) 8.65 (2.5, 40.17)
14.0 g EACA IV 22.54 (0.24, 5155.59) 3.89 (0.17, 202.23) 4.05 (0.02, 1091.86) 12.99 (0.12, 2905.01) 1 114.61 (1.46, 23256.29)
Placebo 0.2 (0.06, 0.65) 0.04 (0, 0.69) 0.03 (0, 6.04) 0.12 (0.02, 0.4) 0.01 (0, 0.68) 1

Note: Bold results mean statistically significance.

Abbreviations: IA, intra‐articular; TXA, tranexamic acid; EACA, aminocaproic acid.