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. 2023 Mar 6;15(4):930–946. doi: 10.1111/os.13678

TABLE 15.

Matrix of pairwise comparisons on PE/DVT rates in intravenous(mg/kg) administration (shown as odds ratios and 95% confidence intervals)

10 mg/kg TXA IV 150 mg/kg EACA IV 15 mg/kg TXA IV 20 mg/kg TXA IV 30 mg/kg TXA IV Placebo
10 mg/kg TXA IV 1 1.48 (0.06, 26.35) 1.01 (0.38, 2.72) 0.86 (0.19, 4.17) 1.35 (0.34, 5.2) 1.13 (0.43, 2.81)
150 mg/kg EACA IV 0.68 (0.04, 15.9) 1 0.68 (0.04, 15.73) 0.58 (0.04, 13.02) 0.89 (0.05, 24.36) 0.75 (0.05, 15.78)
15 mg/kg TXA IV 0.99 (0.37, 2.65) 1.46 (0.06, 23.41) 1 0.86 (0.19, 3.66) 1.34 (0.4, 4.18) 1.12 (0.51, 2.37)
20 mg/kg TXA IV 1.16 (0.24, 5.2) 1.73 (0.08, 27.82) 1.16 (0.27, 5.18) 1 1.58 (0.3, 7.34) 1.3 (0.37, 4.75)
30 mg/kg TXA IV 0.74 (0.19, 2.9) 1.12 (0.04, 18.8) 0.74 (0.24, 2.48) 0.63 (0.14, 3.33) 1 0.83 (0.29, 2.49)
Placebo 0.88 (0.36, 2.33) 1.34 (0.06, 18.63) 0.89 (0.42, 1.95) 0.77 (0.21, 2.7) 1.21 (0.4, 3.43) 1

Abbreviations: IA, intra‐articular; TXA, tranexamic acid; EACA, aminocaproic acid.