Table 4.
Studies with changes in body composition induced by consumption of hydrolyzed collagen.
| Collagen | Design | Population (n) | Period | Dose/day | Result | Reference |
|---|---|---|---|---|---|---|
| SCP | D-RCT | Postmenopausal women 64.3 ± 7.2 years (102) | 48 weeks | 5 g | ↑BMD of the spine and femoral neck; ↑P1NP | [61] |
| SCP | D-RCT | Pre-menopausal women 29–48 years (77) | 12 weeks | 15 g | ↑muscle mass; ↑ hand pressure strength; ↓FM; ↑ leg strength gain | [77] |
| CP | D-RCT | Recreationally active young men 24 ± 3 years (57) | 12 weeks | 15 g | ↑muscle mass; ↑strength; ↔fCSA | [78] |
| CP | D-RCT | Young men 24.2 ± 2.6 years (25) | 12 weeks | 15 g | ↑muscle mass; ↑strength; ↑body mass; ↑ proteins related to contractile fibers | [79] |
| CP | D-RCT | Elderly people 72.2 ± 4.7 years with sarcopenia (53) | 12 weeks | 15 g | ↑muscle mass; ↑IQS; ↑muscle strength; ↑ loss of FM | [80] |
↑: increase; ↓: decrease; ↔: no difference; D-RCT: randomized, double-blind clinical trial; CP: collagen peptides; SCP: specific collagen peptides; BMD: bone mineral density; P1NP: terminal propeptides of type 1 pro-collagen phosphatase; P1NP: amino-terminal propeptide of type I collagen; FM: Fat mass; IQS: isokinetic quadriceps strength; fCSA: muscle fiber cross-sectional area.