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. 2023 Mar 31;14:1142374. doi: 10.3389/fphar.2023.1142374

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Copyright © 2023 Li, Chen, Ma, Du and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of four nanomedicines. (A,B) Hydrodynamic diameters of NP/siNC, NP/siCD47, NP/R848/siNC, and NP/R848/siCD47. (C,D) Zeta potential of NP/siNC, NP/siCD47, NP/R848/siNC, and NP/R848/siCD47. (E) RNA agarose gel electrophoresis. The un-encapsulated siRNA during the preparation of the NP/siNC, NP/siCD47, NP/R848/siNC, and NP/R848/siCD47 was measured by RNA agarose gel electrophoresis. (F) siRNA-loading efficiencies of NP/siNC, NP/siCD47, NP/R848/siNC, and NP/R848/siCD4. (G) Scanning electron microscopic (SEM) image of NP/siNC, NP/siCD47, NP/R848/siNC, and NP/R848/siCD47. The scale bar is shown in the figure. Data were presented as mean ± SEM (n = 5).