Table 4.
Subgroup analyses of the associations between serum selenium concentrations and all-cause mortality among CKD patientsa.
| Characteristics | Serum selenium concentration (μg/L) | ||||
|---|---|---|---|---|---|
| Q1<156.1 | Q2 156.1–181.7 | Q3 181.7–201.5 | Q4 201.5–734.8 | P -trend | |
| Age, y | |||||
| <65 | 1 | 0.836 (0.523, 1.337) | 0.605 (0.36, 1.015) | 0.493 (0.296, 0.82) | 0.003262 |
| ≥65 | 1 | 0.902 (0.742, 1.096) | 0.798 (0.631, 1.008) | 0.748 (0.585, 0.955) | 0.007641 |
| Sex | |||||
| Male | 1 | 1.070 (0.846, 1.352) | 0.718 (0.535, 0.964) | 0.643 (0.478, 0.865) | 0.00109 |
| Female | 1 | 0.675 (0.508, 0.897) | 0.787 (0.576, 1.075) | 0.797 (0.572, 1.111) | 0.07929 |
| Ethnicity (%) | |||||
| Non-Hispanic white | 1 | 0.987 (0.786, 1.239) | 0.739 (0.563, 0.97) | 0.696 (0.529, 0.915) | 0.00289 |
| Other | 1 | 0.701 (0.524, 0.937) | 0.685 (0.485, 0.968) | 0.644 (0.443, 0.936) | 0.00813 |
| BMI, kg/m2 | |||||
| <30 | 1 | 0.922 (0.739, 1.151) | 0.727 (0.547, 0.967) | 0.765 (0.58, 1.009) | 0.014546 |
| ≥30 | 1 | 0.794 (0.585, 1.077) | 0.738 (0.531, 1.025) | 0.560 (0.389, 0.807) | 0.00147 |
| Smoking status | |||||
| Never smoker | 1 | 1.024 (0.777, 1.347) | 0.816 (0.589, 1.13) | 0.738 (0.522, 1.045) | 0.06053 |
| Smoker | 1 | 0.798 (0.63, 1.01) | 0.704 (0.531, 0.933) | 0.651 (0.49, 0.866) | 0.000728 |
a
Cox proportional hazard models were used to estimate the HRs (95% CIs) of all-cause mortality according to quartiles of serum selenium concentrations. Results were adjusted for age (≥65 or <65), sex (male or female), race (non-Hispanic white or other), BMI (≥30 or <30 kg/m2), and smoking status (smoker or never smoker).
BMI, body mass index; Q, quartile.