Table 1.
Profiles of exposure and outcomes in GWAS datasets.
| Outcome | GWAS ID | Consortium | Sample Size | Number of Cases | Number of Controls | Year | Adjustment | Population |
|---|---|---|---|---|---|---|---|---|
| sepsis | ieu-b-4980 | UK Biobank | 486,484 | 11,643 | 474,841 | 2021 | BMI, COPD, fatigue, arteritis, vaginitis, urolithiasis, depression, immunocompromised, LIDI, ISD | European |
| ALRIs | finn-b-J10_LOWERINF | FinnGen biobank | 218,792 | 10,103 | 208,689 | 2021 | ||
| IIs | finn-b-AB1_VIRAL_OTHER_INTEST_INFECTIONS | FinnGen biobank | 201,463 | 4,165 | 197,298 | 2021 | ||
| GUTIs in pregnancy | finn-b-O15_PREG_GU_INFECT | FinnGen biobank | 111,731 | 1,401 | 110,330 | 2021 | ||
| SSTIs | finn-b-L12_INFECT_SKIN | FinnGen biobank | 218,792 | 10,343 | 208,449 | 2021 | ||
| UTIs | ukb-b-8814 | MRC-IEU | 463,010 | 5,447 | 457,563 | 2018 | ||
| Exposure | GWAS ID | Consortium | Sample Size | Number of Cases | Number of Controls | Year | nSNP | Population |
| T1DM | ebi-a-GCST010681 | EBI database | 24,840 | 9,266 | 15,574 | 2020 | 12,783,129 | European |
GWAS, genome-wide association study; ID, identity; nSNP, number of single nucleotide polymorphism; ALRIs, acute lower respiratory infections; IIs, intestinal infections; GUTIs, infections of genitourinary tract; SSTIs, infections of the skin and subcutaneous tissue; UTIs, urinary tract infections; T1DM, type 1 diabetes mellitus; BMI, body mass index; COPD, chronic obstructive pulmonary disease; LIDI, Long-standing illness, disability or infirmity; ISD, Inflammatory skin disease; UK, United Kingdom; MRC-IEU, Medical Research Council Integrative Epidemiology Unit; EBI, European Bioinformatics Institute.