Visualization of the perfusion differences in percentage between SLE and HC for rCBF (top), rCBV (middle) and rMTT (bottom). Only ROIs with a significant perfusion difference i.e., increases of more than 15 % and a decrease of more than −15 %, are shown. An overview of the exact percentages for each ROI can be found in Supplementary Table 1. ROI = Region of interest, SLE = Systemic lupus erythematosus, HC = Healthy Controls, rCBF = Relative cerebral blood flow, rCBV = Relative cerebral blood volume, rMTT = Mean transit time.