Table 2.
NPSLE manifestations among the 64 patients in the SLE cohort, presented as number of patients (percentage of SLE patients), according to three NPSLE attribution models (SLICC A, SLICC B and NPACR).
| SLICC A |
SLICC B |
NPACR |
||
|---|---|---|---|---|
| Patients with NPSLE manifestations | 13 (20 %) | 19 (30 %) | 38 (59 %) | |
| CNS | Cognitive dysfunction | 0 (0 %) | 4 (6 %) | 23 (36 %) |
| Headache | N/A | N/A | 20 (31 %) | |
| Depression | 0 (0 %) | 0 (0 %) | 9 (14 %) | |
| Anxiety | N/A | N/A | 9 (14 %) | |
| Cerebrovascular disease | 1 (2 %) | 4 (6 %) | 4 (6 %) | |
| Acute confusion | 1 (2 %) | 2 (3 %) | 3 (5 %) | |
| Demyelinating disease | 2 (3 %) | 2 (3 %) | 2 (3 %) | |
| Epilepsy | 1 (2 %) | 1 (2 %) | 1 (2 %) | |
| Psychosis | 1 (2 %) | 1 (2 %) | 1 (2 %) | |
| Aseptic meningitis | 1 (2 %) | 1 (2 %) | 1 (2 %) | |
| Chorea | 0 (0 %) | 1 (2 %) | 1 (2 %) | |
| Myelopathy | 0 (0 %) | 1 (2 %) | 1 (2 %) | |
| PNS | Autonomic neuropathy | 7 (11 %) | 8 (13 %) | 10 (16 %) |
| Cranial neuropathy | 5 (8 %) | 5 (8 %) | 5 (8 %) | |
| Mononeuropathy | 1 (2 %) | 2 (3 %) | 2 (3 %) | |
| Polyneuropathy | 1 (2 %) | 1 (2 %) | 2 (3 %) | |
| Plexopathy | 0 (0 %) | 0 (0 %) | 0 (0 %) | |
| Guillain-Barré | 0 (0 %) | 0 (0 %) | 0 (0 %) | |
| Myasthenia Gravis | 0 (0 %) | 0 (0 %) | 0 (0 %) | |
A single patient might present with multiple manifestations, and the patients in SLICC A are by definition also included in SLICC B.
NPSLE = Neuropsychiatric systemic lupus erythematosus, SLICC = Systemic Lupus International Collaborating Clinics, NPACR = American College of Rheumatology case definitions for NPSLE, CNS = Central nervous system, PNS = Peripheral nervous system, N/A = Not applicable.