Table 1.
Demographic and clinical information of the sample. Groups differed significantly in age, but not in sex, days between sessions nor framewise displacement. In the First Episode of Psychosis group (FEP), patients showed statistically significant differences in symptoms severity between sessions 1 and 2 (for PANSS Total scores and independently for each subscale). Not statistically significant changes were found in doses of antipsychotic medication between sessions.
| FEP (N = 30) |
HC (N = 32) |
Statistics | |||
|---|---|---|---|---|---|
| Sess1 | Sess2 | Sess1 | Sess2 | ||
| Sex (F/M) | 8/22 | 13/19 | Chi-square = 1.34 p = 0.246 |
||
| Age (mean ± sd) | 20.4 ± 2.57 | 24.06 ± 3.56 | t = − 4.62 p = 2.12e-05 |
||
|
Days of treatment before first session (mean ± sd) |
23.83 ± 10.69 | NA | NA | ||
|
Days between sessions 1 and 2 (mean ± sd) |
122.6 ± 44.22 (17.51 ± 6.31 weeks) |
128.87 ± 47.59 (18.3 ± 6.83 weeks) |
t = 0.52 p = 0.605 |
||
| PANSS Total score (mean ± sd) | 68.83 ± 13.20 | 45.86 ± 15.27 | NA | NA | t = 6.23 p = 5.62e-08 |
|
PANSS Positive scale (mean ± sd) |
16.33 ± 6.18 | 10.10 ± 5.03 | NA | NA |
t = 4.29 p = 6.93e-05 |
|
PANSS Negative scale (mean ± sd) |
19.93 ± 7.43 | 13.33 ± 7.13 | NA | NA | t = 3.51 p = 8.68e-04 |
|
PANSS General scale (mean ± sd) |
32.57 ± 6.69 | 22.43 ± 6.31 | NA | NA | t = 6.04 p = 1.18e-07 |
| Antipsychotic (AP) medication doses (CPZ equivalents in mg) | 510.0 ± 303.81 | 450.36 ± 268.49 | NA | NA | t = 0.79 p = 0.433 |
| Mean Framewise Displacement (mean ± sd) | 0.325 ± 0.129 | 0.318 ± 0.118 | 0.282 ± 0.071 | 0.322 ± 0.117 | t (FEPsess1, HCsess1) = 1.64 p = 0.106 t (FEPsess2, HCsess2) = -0.14 p = 0.885 |
NA = Not Applicable. FEP = First Episode of Psychosis. HC = Healthy Controls.