Table 1.

Multisystem complications of brucellosis and their involvement/complication rates.

System	Complications	complication rate	Original Citation
Motion-osteoarticular system	Spondylitis	2-60%	(Unuvar et al., 2019)
	Sacroiliac arthritis	2-45%	(Unuvar et al., 2019)
	Peripheral arthritis	14-26%	(Unuvar et al., 2019)
	Intervertebral discitis	NA	(Charalambides et al., 2010)
Digestive System	Enlarged liver and spleen	50%	(Dean et al., 2012)
	Liver abscess	NA	(Le Moigne et al., 2016)
	Splenic abscess	NA	(Deveer et al., 2013)
	Acute cholecystitis	NA	(Hariz et al., 2019)
	Acute pancreatitis	NA	(Berber et al., 2014)
Respiratory System	Pneumonia	NA	(Erdem et al., 2014)
Genitourinary system	Epididymo-orchitis	2-20%	(Batirel et al., 2020)
Cardiovascular System	Endocarditis	2%	(Ece et al., 2020)
	Arrhythmia or coronary ischemia	28.7%	(Lu et al., 2021)
blood system	Anemia	20-53%	(Justman et al., 2018)
	Leukopenia	8-38%	(Justman et al., 2018)
	Thrombocytopenia	2–16%	(Justman et al., 2018)
	Complete blood cytopenia	10%	(Justman et al., 2018)
	HLH	NA	(Mittal et al., 2021)
Nervous System	Meningitis	0.5–25%	(Gul et al., 2009; Díaz-Vintimilla et al., 2021; Kanjo et al., 2021)
Other	skin lesion	5-17%	(Al Jasser and Al Ajroush, 2012; Uçmak et al., 2014)
	Ocular brucellosis	3.4%	(Rolando et al., 2008)
	Thyroiditis	NA	(Cvetkova et al., 2019)

NA means not applicable.