Table 4.
Protection against all cholera and severe cholera episodes by receipt of 2 doses versus no OCV or by residence in Better or Not Better WASH households in the population evaluated for total OCV protection.
| Participants (n) |
Case episodes;100000PY* | Incidence (Cases per 100,000 PY*; 95%CI) |
p-value II (Trend test) |
Crude PE# (95%CI) | p-value | Adjusted PE# (95%CI) |
p-value | |
|---|---|---|---|---|---|---|---|---|
| All cholera | ||||||||
| Residence in control clusters | 78,518 | 222;105657 | 210 (183,238) |
Ref. | – | Ref. | – | |
| Receipt of OCV | 61,970 | 97;79032 | 123 (98,147) |
<0.001 | 41 (20,57) | 0.001 | 40 (21,54) ƪ | <0.001 |
| All cholera | ||||||||
| Residence in not Better WASH households | 103,400 | 251;135602 | 185 (162,208) |
Ref. | – | Ref. | – | |
| Residence in Better WASH households | 37,088 | 68;49087 | 139 (106,171) |
0.033 | 25 (-1,45) | 0.057 | 26 (0,46) 
|
0.051 |
| Severe cholera | ||||||||
| Residence in control clusters | 78,518 | 105;105723 | 99 (80,118) |
Ref. | – | Ref. | – | |
| Receipt of OCV | 61,970 | 34;79073 | 43 (29,57) |
<0.001 | 57 (32,72) | <0.001 | 55 (32,70) ¶ | <0.001 |
| Severe cholera | ||||||||
| Residence in Not Better WASH households | 103,400 | 116;135677 | 85 (70,101) |
Ref. | – | Ref. | – | |
| Residence in Better WASH households | 37,088 | 23;49119 | 47 (28,66) |
0.007 | 45 (20,63) | 0.002 | 33 (5,53) § | 0.024 |
* Person-years.
Adjusted for closer distance from the household to the nearest icddr,b hospital, age at zero time (years), household average expenditure, individuals living in a household with a concrete roof, individuals having reported diarrhea within 6 months at the time of household registration, the total number of household members, individuals household wash status, receipt of 2-doses of OCV.
Protective effectiveness.
One-sided p-value calculated using Cochran–Armitage test.
Adjusted for closer distance from the household to the nearest icddr,b hospital, age at zero time (years), household average expenditure, individuals living in a household with a concrete roof, individuals having reported diarrhea within 6 months at the time of household registration, total number of household members, individuals household wash status, household wash status.
Adjusted for closer distance from the household to the nearest icddr,b hospital, age at zero time (years), household average expenditure, individuals living in their own house, individuals living in a household with only one room, individuals having reported diarrhoea within 6 months at the time of household registration, total number of household members, household wash status.
Adjusted for closer distance from the household to the nearest icddr,b hospital, age at zero time (years), household average expenditure, individuals living in their own house, individuals living in a household with only one room, individuals having reported diarrhoea within 6 months at the time of household registration, total number of household members, receipt of 2-doses of OCV.