Table 5. Predictive performance for parameters in identifying high-proliferation and low-proliferation endometrial carcinoma.
| Parameter | AUC (95% CI) | P value | Cutoff | Sensitivity (%) | Specificity (%) | Versus combined diagnosis (D + Kep) |
|---|---|---|---|---|---|---|
| D (×10−3 mm2/s) | 0.753 (0.636–0.849) | <0.001 | 0.695 | 71.43 | 67.86 | Z=2.874, P=0.004 |
| D* (×10−3 mm2/s) | 0.536 (0.416–0.653) | 0.598 | – | – | – | – |
| f (%) | 0.538 (0.415–0.658) | 0.605 | – | – | – | – |
| α | 0.715 (0.595–0.817) | <0.001 | 0.691 | 47.62 | 89.29 | Z=3.505, P=0.001 |
| DDC (×10−3 mm2/s) | 0.606 (0.482–0.721) | 0.133 | – | – | – | – |
| Ktrans (min–1) | 0.808 (0.696–0.892) | <0.001 | 0.743 | 57.14 | 96.43 | Z=2.741, P=0.006 |
| Ve | 0.607 (0.483–0.721) | 0.120 | – | – | – | – |
| Kep (min–1) | 0.832 (0.724–0.911) | 0.204 | 1.237 | 71.43 | 82.14 | Z=2.147, P=0.032 |
| Combined diagnosis (D + Kep) | 0.920 (0.830–0.971) | <0.001 | – | 85.71 | 89.29 | – |
D, diffusion coefficient; D*, pseudo diffusion coefficient; f, perfusion fraction; α, water molecular diffusion heterogeneity index; DDC, distributed diffusion coefficient; Ktrans, volume transfer constant; Ve, volume of extravascular extracellular space per unit volume of tissue; Kep, rate transfer constant; AUC, area under the receiver operating characteristic curve; CI, confidence interval.