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. 2022 Aug 18;13(4):2697–2707. doi: 10.21037/qims-22-172

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2023 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A 44-year-old female with thyroid adenoma (arrow) in the right thyroid lobe. (A) Axial T2-WI showed a 28-mm solid nodule with a regular margin and a negative taller-than-wide sign: the SIR was 4.58. (B) Axial T1-WI: the SIR was 1.33. (C) ADC map; ADC value =2.78×10⁻³ mm²/s. (D) MD map; MD value =3.05×10⁻³ mm²/s. (E) MK map; MK value =0.39. (F) Histopathological HE staining (×40). T2WI, T2-weighted imaging; SIR, signal intensity ratio; T1WI, T1-weighted imaging; ADC, apparent diffusion coefficient; MD, mean diffusivity; MK, mean kurtosis; HE, hematoxylin and eosin.