Table 2.
Data analysis, top ten imaging features (for each subgroup), and their estimated main effects and interactions
| Image feature | Main effect | Interaction with | |||
|---|---|---|---|---|---|
| age | sex | smoking | stage | ||
| Subgroup 1 | |||||
| Texture_Variance_ImageAfterMath_3_03 | 37.751 | –22.214 | |||
| Texture_InverseDifferenceMoment_ImageAfterMath_3_03 | 6.016 | ||||
| Texture_InfoMeas1_ImageAfterMath_3_03 | 34.927 | –2.519 | –34.746 | 9.512 | 1.343 |
| Texture_AngularSecondMoment_ImageAfterMath_3_02 | –3.738 | ||||
| Neighbors_NumberOfNeighbors_Adjacent | –8.971 | ||||
| ModuleError_11IdentifyPrimaryObjects | 15.694 | ||||
| Granularity_4_ImageAfterMath | 1.488 | ||||
| Granularity_15_ImageAfterMath.1 | –103.689 | ||||
| Granularity_10_ImageAfterMath | –12.48 | ||||
| AreaShape_Zernike_8_0 | 22.888 | –30.9 | |||
| Subgroup 2 | |||||
| Texture_InverseDifferenceMoment_ImageAfterMath_3_03 | 3.995 | ||||
| Neighbors_NumberOfNeighbors_Adjacent | –0.958 | ||||
| Metadata_Series | –100.833 | 1.262 | 100.984 | 1.417 | 0.111 |
| Granularity_8_ImageAfterMath.1 | 5.579 | ||||
| Granularity_7_ImageAfterMath | –1.818 | ||||
| Granularity_6_ImageAfterMath | –9.533 | ||||
| Granularity_1_ImageAfterMath.1 | 6.934 | ||||
| ExecutionTime_13MaskImage | –11.893 | ||||
| Count_Identifyeosinprimarycytoplasm | –4.64 | ||||
| AreaOccupied_AreaOccupied_Identifyeosinprimarycytoplasm | 0.84 | 9.394 | |||