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. 2023 Apr 13;141(5):441–447. doi: 10.1001/jamaophthalmol.2023.0610

Table 1. Propensity Score Matching Results Between First- and Second-Dose COVID-19 Vaccine Cohort.

Characteristic Before matching After matching
COVID-19 dose, No. (%) SMD COVID-19 dose, No. (%) SMD
First (n = 3 108 829) Second (n = 1 180 006) First (n = 1 180 006) Second (n = 1 180 006)
Age at vaccination, mean (SD), y 50.7 (20.4) 52.2 (20.6) 0.074 52.2 (20.6) 52.2 (20.6) <0.001
Sexa
Female 1 753 009 (56.4) 660 796 (56.0) 0.008 660 796 (56.0) 660 796 (56.0) <0.001
Male 1 354 008 (43.6) 518 105 (43.9) 0.007 518 119 (43.9) 518 3105 (43.9) <0.001
Ethnicityb
Hispanic or Latinx 296 919 (9.6) 162 950 (13.8) 0.133 162 929 (13.8) 162 950 (13.8) <0.001
Not Hispanic or Latinx 1 812 998 (58.3) 882 568 (74.8) 0.355 882 589 (74.8) 882 568 (74.8) <0.001
Unknown 998 912 (32.1) 134 488 (11.4) 0.519 134 488 (11.4) 134 488 (11.4) <0.001
Raceb
Asian 136 455 (4.4) 72 120 (6.1) 0.077 72 109 (6.1) 72 120 (6.1) <0.001
Black or African American 370 356 (11.9) 179 490 (15.2) 0.096 179 498 (15.2) 179 490 (15.2) <0.001
Native Hawaiian or Pacific Islander 5053 (0.2) 2362 (0.2) 0.009 2344 (0.2) 2362 (0.2) <0.001
White 2 001 510 (64.4) 773 904 (65.6) 0.025 773 925 (65.6) 773 904 (65.6) <0.001
Unknown 578 694 (18.6) 144 904 (12.3) 0.176 144 928 (12.3) 144 904 (12.3) <0.001
Comorbidities
Diabetes 384 601 (12.4) 147 591 (12.5) 0.004 147 550 (12.5) 147 591 (12.5) <0.001
Hypertension 871 147 (28.0) 332 131 (28.1) 0.003 332 095 (28.1) 332 131 (28.1) <0.001
Hyperlipidemia 623 080 (20.0) 220 112 (18.7) 0.035 220 071 (18.6) 220 112 (18.7) <0.001

Abbreviation: SMD, standardized mean difference.

a

Some data not reported.

b

Race and ethnicity were determined based on the presence of these designations within the electronic health record.