Table 1. Propensity Score Matching Results Between First- and Second-Dose COVID-19 Vaccine Cohort.
Characteristic | Before matching | After matching | ||||
---|---|---|---|---|---|---|
COVID-19 dose, No. (%) | SMD | COVID-19 dose, No. (%) | SMD | |||
First (n = 3 108 829) | Second (n = 1 180 006) | First (n = 1 180 006) | Second (n = 1 180 006) | |||
Age at vaccination, mean (SD), y | 50.7 (20.4) | 52.2 (20.6) | 0.074 | 52.2 (20.6) | 52.2 (20.6) | <0.001 |
Sexa | ||||||
Female | 1 753 009 (56.4) | 660 796 (56.0) | 0.008 | 660 796 (56.0) | 660 796 (56.0) | <0.001 |
Male | 1 354 008 (43.6) | 518 105 (43.9) | 0.007 | 518 119 (43.9) | 518 3105 (43.9) | <0.001 |
Ethnicityb | ||||||
Hispanic or Latinx | 296 919 (9.6) | 162 950 (13.8) | 0.133 | 162 929 (13.8) | 162 950 (13.8) | <0.001 |
Not Hispanic or Latinx | 1 812 998 (58.3) | 882 568 (74.8) | 0.355 | 882 589 (74.8) | 882 568 (74.8) | <0.001 |
Unknown | 998 912 (32.1) | 134 488 (11.4) | 0.519 | 134 488 (11.4) | 134 488 (11.4) | <0.001 |
Raceb | ||||||
Asian | 136 455 (4.4) | 72 120 (6.1) | 0.077 | 72 109 (6.1) | 72 120 (6.1) | <0.001 |
Black or African American | 370 356 (11.9) | 179 490 (15.2) | 0.096 | 179 498 (15.2) | 179 490 (15.2) | <0.001 |
Native Hawaiian or Pacific Islander | 5053 (0.2) | 2362 (0.2) | 0.009 | 2344 (0.2) | 2362 (0.2) | <0.001 |
White | 2 001 510 (64.4) | 773 904 (65.6) | 0.025 | 773 925 (65.6) | 773 904 (65.6) | <0.001 |
Unknown | 578 694 (18.6) | 144 904 (12.3) | 0.176 | 144 928 (12.3) | 144 904 (12.3) | <0.001 |
Comorbidities | ||||||
Diabetes | 384 601 (12.4) | 147 591 (12.5) | 0.004 | 147 550 (12.5) | 147 591 (12.5) | <0.001 |
Hypertension | 871 147 (28.0) | 332 131 (28.1) | 0.003 | 332 095 (28.1) | 332 131 (28.1) | <0.001 |
Hyperlipidemia | 623 080 (20.0) | 220 112 (18.7) | 0.035 | 220 071 (18.6) | 220 112 (18.7) | <0.001 |
Abbreviation: SMD, standardized mean difference.
Some data not reported.
Race and ethnicity were determined based on the presence of these designations within the electronic health record.