Table 3. Propensity Score Matching Results Between First-Dose COVID-19 Vaccine Cohort and Tdap Vaccine Cohort.
Characteristic | Before matching | After matching | ||||
---|---|---|---|---|---|---|
No. (%) | SMD | No. (%) | SMD | |||
First dose COVID-19 (n = 3 108 829) | Tdap (n = 743 991) | First dose COVID-19 (n = 718 400) | Tdap (n = 718 400) | |||
Age at vaccination, mean (SD), y | 50.7 (20.4) | 38.1 (20.1) | 0.617 | 39.8 (19.1) | 39.1 (19.8) | 0.034 |
Sexa | ||||||
Female | 1 753 009 (56.4) | 416 429 (56.0) | 0.008 | 400 606 (55.8) | 407 135 (56.7) | 0.018 |
Male | 1 354 008 (43.6) | 327 454 (44.0) | 0.009 | 317 639 (44.2) | 311 157 (43.3) | 0.018 |
Ethnicityb | ||||||
Hispanic or Latinx | 296 919 (9.6) | 68 999 (9.3) | 0.009 | 63 406 (8.8) | 68 924 (9.6) | 0.027 |
Not Hispanic or Latinx | 1 812 998 (58.3) | 481 661 (64.7) | 0.132 | 475 534 (66.2) | 458 588 (63.8) | 0.049 |
Unknown | 998 912 (32.1) | 193 331 (26.0) | 0.136 | 179 460 (25.0) | 190 888 (26.6) | 0.036 |
Raceb | ||||||
Asian | 136 455 (4.4) | 26 299 (3.5) | 0.044 | 25 590 (3.6) | 26 299 (3.7) | 0.005 |
Black or African American | 370 356 (11.9) | 132 602 (17.8) | 0.167 | 131 764 (18.3) | 121 309 (16.9) | 0.038 |
Native Hawaiian or Pacific Islander | 5053 (0.2) | 1574 (0.2) | 0.011 | 1669 (0.2) | 1543 (0.2) | 0.004 |
White | 2 001 510 (64.4) | 485 322 (65.2) | 0.018 | 476 199 (66.3) | 471 055 (65.6) | 0.015 |
Unknown | 578 694 (18.6) | 94 552 (12.7) | 0.163 | 80 111 (11.2) | 94 552 (13.2) | 0.062 |
Comorbidities | ||||||
Diabetes | 384 601 (12.4) | 62 119 (8.3) | 0.132 | 66 268 (9.2) | 62 071 (8.6) | 0.02 |
Hypertension | 871 147 (28.0) | 145 859 (19.6) | 0.199 | 153 887 (21.4) | 145 716 (20.3) | 0.028 |
Hyperlipidemia | 623 080 (20.0) | 96 179 (12.9) | 0.193 | 100 469 (14.0) | 96 120 (13.4) | 0.018 |
Abbreviations: SMD, standardized mean difference; Tdap, tetanus, diphtheria, pertussis.
Some data not reported.
Race and ethnicity were determined based on the presence of these designations within the electronic health record.