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a Time-course showing head-twitch (HTR) counts on 15-min blocks in male and female 129S6/SvEv mice injected (i.p.) with DOI (0.5 mg/kg) or vehicle. Black arrow indicates the administration timepoint. b Head-twitch counts corresponding to the first 30 min after injection of DOI or vehicle (n = 6 mice per group). Two-way repeated measures ANOVA (a) and two-way ANOVA (b) followed by Sidak’s multiple comparison test. ***p < 0.001, n.s., not significant
