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Effect of M100,907 (1.0 mg/kg) and DOI (0.5 mg/kg) on startle amplitude (a) and %PPI (b) in male 129S6/SvEv mice. Experimental conditions included a 40-ms pulse at 119 dB; 10 ms prepulse stimulus at 73, 77, and 85 dB; an interstimulus interval of 60 ms; and background noise set to 69 dB (n = 10 mice per group). Two-way ANOVA followed by Sidak’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001, n.s., not significant
